For potential egg donors
Genetic testing of all potential egg donors is a very important part of their screening at Embryolab. The aim is to maximise the chances of a safe pregnancy and therefore, a healthy baby.
All potential donors are assessed for the followings:
Qualitative in-depth and one-to-one interviews are conducted with all egg donors by our in house specialized psychologist. A detailed family history is also registered. Potential egg donors with a family history of disorders such as diabetes, cardiovascular diseases, or various cancers are excluded.
Karyotype testing is performed as part of the initial screening of the egg donors. Less than 5% of all healthy individuals who are carriers of chromosomal abnormalities, may transmit a chromosomal defect through their gametes to the resulting embryos. The result is an increased risk for miscarriages or a chromosomally affected baby. All potential egg donors carrying a chromosomal abnormality are excluded
Thalassaemia and Cystic Fibrosis are two of the most frequent genetic disorders found in the Caucasian population. Despite being healthy, a carrier of one of these gene disorders has a 50% chance of transmitting the defected gene to her/his child. In case that the partner is also a carrier, there is a 25% risk of an affected baby. All egg donors are routinely tested for Thalassaemia and Cystic Fibrosis. Potential donors who are diagnosed to be carriers are excluded.
ADDITIONAL GENETIC SCREENING
FOR SPECIFIC GENE DISORDERS:
Different ethnic groups tend to be carriers of specific hereditary diseases. Genetic tests for specific gene disorders such as Fanconi anemia, Tay-Sachs, Fragile X and hemophilia, may be performed according to the donor’s or the couple’s history and ethnic background.
EXTENSIVE GENETIC CARRIER SCREENING
Each healthy individual may carry a number of rare genetic mutations. Partners carrying mutations in the same gene may have a 25% risk of delivering an affected baby. The candidate donor’s genetic carrier screening test involves the diagnosis of multiple mutations of several hundred genetic diseases. The aim of the extensive screening is to reduce the risk of an affected baby and protect the health of your future family.